Cannot connect to outgoing email server

Cannot connect to your outgoing (SMTP) email server, getting Error 0x80042109
 
The error 0x80042109 is one with Outlook not being able to connect to our mail server to send email. You may want to troubleshoot by temporarily disabling any antivirus application or firewall that may be blocking your traffic. Until you get this figured out, you can send email via webmail. Below are a few articles regarding this problem which may help:

http://support.microsoft.com/?kbid=813514
http://support.microsoft.com/kb/302357
http://www.google.com/search?hl=en&rls=com.microsoft:*&q=0x80042109+outlook+2007&revid=651029601&sa=X&oi=revisions_inline&resnum=0&ct=broad-revision&cd=2

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