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Error: system is not configured to relay mail

QUESTION 
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I'm trying to send from my email account to several addresses that he normally sends to and I'm getting this error message: 

501 5.7.1 Error Message: This system is not configured to relay mail from myname@mydomain.com to specified recipients. 


ANSWER 
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You need to have SMTP Authentication turned on in your email client software. Please refer to our email setup support pages at the URL below for information on how to setup SMTP Authentication for your specific client. 

http://www.interactivevillages.com/support-info/email-32479

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